Paige and Leo (Rachel McAdams and Channing Tatum) are a happy newlywed couple whose lives are changed by a car accident that puts Paige in a coma. Waking up with severe memory loss, Paige has no memory of Leo, a confusing relationship with her parents (Sam Neill and Jessica Lange), and an ex-fiancé (Scott Speedman) she may still have feelings for.

Despite these complications, Leo endeavors to win her heart again and rebuild their marriage.